6OO9
Human CYP3A4 bound to a drug mibefradil
Summary for 6OO9
Entry DOI | 10.2210/pdb6oo9/pdb |
Descriptor | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate, ... (6 entities in total) |
Functional Keywords | substrate, complex, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 57072.20 |
Authors | Sevrioukova, I.F. (deposition date: 2019-04-22, release date: 2019-09-11, Last modification date: 2023-10-11) |
Primary citation | Sevrioukova, I.F. Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin. Int J Mol Sci, 20:-, 2019 Cited by PubMed: 31480231DOI: 10.3390/ijms20174245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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