6OL2

Crystallography of novel WNK1 and WNK3 inhibitors discovered from high-throughput-screening

6OL2 の概要

• エントリーDOI: 10.2210/pdb6ol2/pdb
• 分子名称: Serine/threonine-protein kinase WNK1, N-[2-(5,8-dimethoxy-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]-2-iodobenzamide, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34505.28

構造登録者

Chlebowicz, J.,Akella, R.,Sekulski, K.,Humphreys, J.M.,Durbacz, M.Z.,He, H.,Rodan, A.,Posner, B.,Goldsmith, E.J. (登録日: 2019-04-15, 公開日: 2020-04-15, 最終更新日: 2023-10-11)

• 主引用文献: Chlebowicz, J.,Akella, R.,Sekulski, K.,Humphreys, J.M.,Durbacz, M.Z.,He, H.,Rodan, A.,Posner, B.,Goldsmith, E.J.; Crystallography of novel WNK1 and WNK3 inhibitors discovered from high throughput screening; To Be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)