6OKD

Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide

6OKD の概要

• エントリーDOI: 10.2210/pdb6okd/pdb
• 分子名称: Transferrin receptor protein 1, transferrin receptor binding cystine-dense peptide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total)
• 機能のキーワード: protein-protein complex, cystine-dense peptide, transport protein-signaling protein complex, transport protein/signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 164220.86

構造登録者

Finton, K.A.K.,Rupert, P.B.,Strong, R.K. (登録日: 2019-04-12, 公開日: 2020-04-15, 最終更新日: 2023-10-11)

• 主引用文献: Crook, Z.R.,Girard, E.,Sevilla, G.P.,Merrill, M.,Friend, D.,Rupert, P.B.,Pakiam, F.,Nguyen, E.,Yin, C.,Ruff, R.O.,Hopping, G.,Strand, A.D.,Finton, K.A.K.,Coxon, M.,Mhyre, A.J.,Strong, R.K.,Olson, J.M.; A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules.; J.Mol.Biol., 432:3989-4009, 2020; PubMed: 32304700; DOI: 10.1016/j.jmb.2020.04.002

実験手法

X-RAY DIFFRACTION (1.85 Å)