6OGE

Cryo-EM structure of Her2 extracellular domain-Trastuzumab Fab-Pertuzumab Fab complex

Summary for 6OGE

• Entry DOI: 10.2210/pdb6oge/pdb
• EMDB information: 20055
• Descriptor: Receptor tyrosine-protein kinase erbB-2, Pertuzumab FAB LIGHT CHAIN, Pertuzumab FAB HEAVY CHAIN, ... (7 entities in total)
• Functional Keywords: her2 extracellular domain, trastuzumab, pertuzumab, transferase-immune system complex, transferase/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 164505.42

Authors

Hao, Y.,Yu, X.,Bai, Y.,Huang, X. (deposition date: 2019-04-02, release date: 2019-05-15, Last modification date: 2020-07-29)

• Primary citation: Hao, Y.,Yu, X.,Bai, Y.,McBride, H.J.,Huang, X.; Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex.; Plos One, 14:e0216095-e0216095, 2019; PubMed: 31042744; DOI: 10.1371/journal.pone.0216095

Experimental method

ELECTRON MICROSCOPY (4.36 Å)