6OFI
CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120
Summary for 6OFI
Entry DOI | 10.2210/pdb6ofi/pdb |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, CH55 Fab heavy chain, CH55 Fab light chain, ... (4 entities in total) |
Functional Keywords | anti-hiv-1 env antibody ch55, cd4i antibody, adcc, hiv-1 env, immune system, rv144 vaccine trial, clade a/e 93th057, viral protein-immune system complex |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 89017.69 |
Authors | Tolbert, W.D.,Yan, F.,Van, V.,Pazgier, M. (deposition date: 2019-03-29, release date: 2020-06-24, Last modification date: 2023-10-11) |
Primary citation | Tolbert, W.D.,Van, V.,Sherburn, R.,Tuyishime, M.,Yan, F.,Nguyen, D.N.,Stanfield-Oakley, S.,Easterhoff, D.,Bonsignori, M.,Haynes, B.F.,Moody, M.A.,Ray, K.,Ferrari, G.,Lewis, G.K.,Pazgier, M. Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial. Mbio, 11:-, 2020 Cited by PubMed: 32605979DOI: 10.1128/mBio.00208-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.85 Å) |
Structure validation
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