6OF5
The crystal structure of dodecyloxy(naphthalen-1-yl)methylphosphonic acid in complex with red kidney bean purple acid phosphatase
Summary for 6OF5
Entry DOI | 10.2210/pdb6of5/pdb |
Descriptor | Fe(3+)-Zn(2+) purple acid phosphatase, SODIUM ION, 1,2-ETHANEDIOL, ... (15 entities in total) |
Functional Keywords | purple acid phosphatase, metallohydrolases, transition state, catalysis, osteoporosis, metal binding protein |
Biological source | Phaseolus vulgaris (Kidney bean) |
Total number of polymer chains | 4 |
Total formula weight | 210944.78 |
Authors | Feder, D.,Schenk, G.,Guddat, L.W.,Hussein, W.M.,McGeary, R.P. (deposition date: 2019-03-28, release date: 2019-09-04, Last modification date: 2023-10-11) |
Primary citation | Feder, D.,Kan, M.W.,Hussein, W.M.,Guddat, L.W.,Schenk, G.,McGeary, R.P. Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis. Eur.J.Med.Chem., 182:111611-111611, 2019 Cited by PubMed: 31445230DOI: 10.1016/j.ejmech.2019.111611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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