6OE8
The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C
Summary for 6OE8
Entry DOI | 10.2210/pdb6oe8/pdb |
Descriptor | Uricase, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | uricase, arthrobacter globiformis, thermostability, disulfide cross-linking, oxidoreductase |
Biological source | Arthrobacter globiformis |
Total number of polymer chains | 4 |
Total formula weight | 149435.47 |
Authors | |
Primary citation | Shi, Y.,Wang, T.,Zhou, X.E.,Liu, Q.F.,Jiang, Y.,Xu, H.E. Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy. Acta Pharmacol.Sin., 40:1364-1372, 2019 Cited by PubMed: 31253939DOI: 10.1038/s41401-019-0269-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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