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6OE8

The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C

Summary for 6OE8
Entry DOI10.2210/pdb6oe8/pdb
DescriptorUricase, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywordsuricase, arthrobacter globiformis, thermostability, disulfide cross-linking, oxidoreductase
Biological sourceArthrobacter globiformis
Total number of polymer chains4
Total formula weight149435.47
Authors
Shi, Y.,Wang, T.,Zhou, X.E.,Liu, Q.,Jiang, Y.,Xu, H.E. (deposition date: 2019-03-27, release date: 2019-08-21, Last modification date: 2023-10-11)
Primary citationShi, Y.,Wang, T.,Zhou, X.E.,Liu, Q.F.,Jiang, Y.,Xu, H.E.
Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy.
Acta Pharmacol.Sin., 40:1364-1372, 2019
Cited by
PubMed: 31253939
DOI: 10.1038/s41401-019-0269-x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

217157

数据于2024-03-13公开中

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