6OE5

Splayed open prefusion RSV F captured by CR9501 and motavizumab Fabs

6OE5 の概要

• エントリーDOI: 10.2210/pdb6oe5/pdb
• 分子名称: Fusion glycoprotein F0,Fibritin, Motavizumab Fab Heavy Chain, Motavizumab Fab Light Chain, ... (5 entities in total)
• 機能のキーワード: class i fusion glycoprotein, immunoglobulin, respiratory syncytial virus, trimerization, neutralizing, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human respiratory syncytial virus A (strain A2); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 156729.87

構造登録者

Gilman, M.S.A.,McLellan, J.S. (登録日: 2019-03-27, 公開日: 2019-04-17, 最終更新日: 2020-01-01)

• 主引用文献: Gilman, M.S.A.,Furmanova-Hollenstein, P.,Pascual, G.,B van 't Wout, A.,Langedijk, J.P.M.,McLellan, J.S.; Transient opening of trimeric prefusion RSV F proteins.; Nat Commun, 10:2105-2105, 2019; PubMed: 31068578; DOI: 10.1038/s41467-019-09807-5

実験手法

X-RAY DIFFRACTION (4.1 Å)