6OAO

Structure of DBP in complex with human neutralizing antibody 092096

Summary for 6OAO

Entry DOI	10.2210/pdb6oao/pdb
Descriptor	Duffy binding surface protein region II, Antibody 092096 single chain variable fragment, SULFATE ION, ... (4 entities in total)
Functional Keywords	plasmodium, vivax, duffy binding protein, dbp, pvdbp, antibody, neutralizing, inhibition, malaria, invasion, blocking, vaccine, structural vaccinology, cell invasion
Biological source	Plasmodium vivax More
Total number of polymer chains	12
Total formula weight	382281.73
Authors	Urusova, D.,Tolia, N.H. (deposition date: 2019-03-18, release date: 2019-06-12, Last modification date: 2023-10-11)
Primary citation	Urusova, D.,Carias, L.,Huang, Y.,Nicolete, V.C.,Popovici, J.,Roesch, C.,Salinas, N.D.,Witkowski, B.,Ferreira, M.U.,Adams, J.H.,Gross, M.L.,King, C.L.,Tolia, N.H. Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP. Nat Microbiol, 4:1486-1496, 2019 Cited by PubMed: 31133752 DOI: 10.1038/s41564-019-0461-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.497 Å)

Structure validation