6OAO

Structure of DBP in complex with human neutralizing antibody 092096

6OAO の概要

• エントリーDOI: 10.2210/pdb6oao/pdb
• 分子名称: Duffy binding surface protein region II, Antibody 092096 single chain variable fragment, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: plasmodium, vivax, duffy binding protein, dbp, pvdbp, antibody, neutralizing, inhibition, malaria, invasion, blocking, vaccine, structural vaccinology, cell invasion
• 由来する生物種: Plasmodium vivax; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 382281.73

構造登録者

Urusova, D.,Tolia, N.H. (登録日: 2019-03-18, 公開日: 2019-06-12, 最終更新日: 2023-10-11)

• 主引用文献: Urusova, D.,Carias, L.,Huang, Y.,Nicolete, V.C.,Popovici, J.,Roesch, C.,Salinas, N.D.,Witkowski, B.,Ferreira, M.U.,Adams, J.H.,Gross, M.L.,King, C.L.,Tolia, N.H.; Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.; Nat Microbiol, 4:1486-1496, 2019; PubMed: 31133752; DOI: 10.1038/s41564-019-0461-2

実験手法

X-RAY DIFFRACTION (3.497 Å)