6O9W

Crystal structure of Staphylococcus aureus BlaR1 antibiotic-sensor domain in complex with avibactam

6O9W の概要

• エントリーDOI: 10.2210/pdb6o9w/pdb
• 分子名称: Regulatory protein BlaR1, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
• 機能のキーワード: beta-lactam antibiotic sensor domain, antibiotic complex, penicillin binding protein, signaling protein
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61365.05

構造登録者

Alexander, J.A.N.,Strynadka, N.C.J. (登録日: 2019-03-15, 公開日: 2020-06-10, 最終更新日: 2023-10-11)

• 主引用文献: Alexander, J.A.N.,Radaeva, M.,King, D.T.,Chambers, H.F.,Cherkasov, A.,Chatterjee, S.S.,Strynadka, N.C.J.; Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus .; J.Biol.Chem., 295:10870-10884, 2020; PubMed: 32518158; DOI: 10.1074/jbc.RA120.013029

実験手法

X-RAY DIFFRACTION (1.95 Å)