6O83

S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic

6O83 の概要

• エントリーDOI: 10.2210/pdb6o83/pdb
• 関連するPDBエントリー: 4ii3 6O82
• 分子名称: Ubiquitin-activating enzyme E1 1, Ubiquitin-60S ribosomal protein L40, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: thioester, adenylation, inhibitor, tetrahedral intermediate, ligase, nucleus, phosphoprotein, ubl conjugation pathway, atp-binding, nucleotide-binding, isopeptide bond, ligase-protein binding complex, ligase/protein binding
• 由来する生物種: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 242950.71

構造登録者

Hann, Z.S.,Lima, C.D. (登録日: 2019-03-08, 公開日: 2019-06-19, 最終更新日: 2023-10-11)

• 主引用文献: Hann, Z.S.,Ji, C.,Olsen, S.K.,Lu, X.,Lux, M.C.,Tan, D.S.,Lima, C.D.; Structural basis for adenylation and thioester bond formation in the ubiquitin E1.; Proc.Natl.Acad.Sci.USA, 116:15475-15484, 2019; PubMed: 31235585; DOI: 10.1073/pnas.1905488116

実験手法

X-RAY DIFFRACTION (3.153 Å)