6O72
Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, TC-I 2014-bound state
Summary for 6O72
Entry DOI | 10.2210/pdb6o72/pdb |
Related | 6O6A 6O6R 6O77 |
EMDB information | 0631 0636 0638 0639 |
Descriptor | Transient receptor potential cation channel subfamily M member 8, CHOLESTEROL HEMISUCCINATE, UNDECANE, ... (6 entities in total) |
Functional Keywords | transport protein, ion channel, trpm8 |
Biological source | Parus major (Great Tit) |
Total number of polymer chains | 4 |
Total formula weight | 515585.20 |
Authors | Diver, M.M.,Cheng, Y.,Julius, D. (deposition date: 2019-03-07, release date: 2019-09-18, Last modification date: 2024-03-20) |
Primary citation | Diver, M.M.,Cheng, Y.,Julius, D. Structural insights into TRPM8 inhibition and desensitization. Science, 365:1434-1440, 2019 Cited by PubMed: 31488702DOI: 10.1126/science.aax6672 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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