X-ray crystal structure of metal-dependent transcriptional regulator MtsR

Summary for 6O5C

DescriptorPutative metal-dependent transcriptional regulator, MANGANESE (II) ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywordsmanganese, transcription regulator, dna binding protein
Biological sourceStreptococcus pyogenes serotype M3
Total number of polymer chains2
Total molecular weight50723.84
Do, H.,Kumaraswami, M. (deposition date: 2019-03-01, release date: 2019-06-12)
Primary citation
Do, H.,Makthal, N.,Chandrangsub, P.,Olsen, R.J.,Helmann, J.D.,Musser, J.M.,Kumaraswami, M.
Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.29350 0.8% 4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution