6O3O

Structure of human DNAM-1 (CD226) bound to nectin-like protein-5 (necl-5)

6O3O の概要

• エントリーDOI: 10.2210/pdb6o3o/pdb
• 分子名称: CD226 antigen, Poliovirus receptor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: immune receptor, immunoglobulin domain, adhesion molecule, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 130501.71

構造登録者

Deuss, F.A.,Watson, G.M.,Rossjohn, J.,Berry, R. (登録日: 2019-02-27, 公開日: 2019-07-10, 最終更新日: 2023-10-11)

• 主引用文献: Deuss, F.A.,Watson, G.M.,Goodall, K.J.,Leece, I.,Chatterjee, S.,Fu, Z.,Thaysen-Andersen, M.,Andrews, D.M.,Rossjohn, J.,Berry, R.; Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1.; J.Biol.Chem., 294:12534-12546, 2019; PubMed: 31253644; DOI: 10.1074/jbc.RA119.009261

実験手法

X-RAY DIFFRACTION (2.8 Å)