6O3L
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
Summary for 6O3L
Entry DOI | 10.2210/pdb6o3l/pdb |
Related | 6O3D 6O3G 6O3J 6O3K 6O3U 6O41 6O42 |
Descriptor | PGZL1.H4K3 light chain, PGZL1.H4K3 heavy chain, MPER peptide, region 671-683 of HIV-1 gp41, ... (6 entities in total) |
Functional Keywords | pgzl1 anti hiv-1, gp41 mper, membrane lipids, broadly neutralising hiv-1 antibody, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 100399.42 |
Authors | Irimia, A.,Wilson, I.A. (deposition date: 2019-02-26, release date: 2019-12-04, Last modification date: 2023-10-11) |
Primary citation | Zhang, L.,Irimia, A.,He, L.,Landais, E.,Rantalainen, K.,Leaman, D.P.,Vollbrecht, T.,Stano, A.,Sands, D.I.,Kim, A.S.,Poignard, P.,Burton, D.R.,Murrell, B.,Ward, A.B.,Zhu, J.,Wilson, I.A.,Zwick, M.B. An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10:5389-5389, 2019 Cited by PubMed: 31772165DOI: 10.1038/s41467-019-12973-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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