6O25
Crystal structure of 3945 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain
Summary for 6O25
Entry DOI | 10.2210/pdb6o25/pdb |
Related | 6O23 6O24 |
Descriptor | 3945 Fab heavy chain, 3945 Kappa light chain, Anti-Kappa VHH domain, ... (5 entities in total) |
Functional Keywords | malaria, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 180054.71 |
Authors | Scally, S.W.,Bosch, A.,Prieto, K.,Murugan, R.,Wardemann, H.,Julien, J.P. (deposition date: 2019-02-22, release date: 2020-07-01, Last modification date: 2024-04-03) |
Primary citation | Murugan, R.,Scally, S.W.,Costa, G.,Mustafa, G.,Thai, E.,Decker, T.,Bosch, A.,Prieto, K.,Levashina, E.A.,Julien, J.P.,Wardemann, H. Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nat. Med., 26:1135-1145, 2020 Cited by PubMed: 32451496DOI: 10.1038/s41591-020-0881-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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