6O0W

Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris

6O0W の概要

• エントリーDOI: 10.2210/pdb6o0w/pdb
• 分子名称: TIR-NB-LRR type resistance protein RUN1, ADENOSINE-2'-5'-DIPHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: plant disease resistance, signaling protein
• 由来する生物種: Vitis rotundifolia (Muscadine grape)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21349.82

構造登録者

Horsefield, S.,Burdett, H.,Zhang, X.,Manik, M.K.,Shi, Y.,Chen, J.,Tiancong, Q.,Gilley, J.,Lai, J.,Gu, W.,Rank, M.,Casey, L.,Ericsson, D.J.,Foley, G.,Hughes, R.O.,Bosanac, T.,von Itzstein, M.,Rathjen, J.P.,Nanson, J.D.,Boden, M.,Dry, I.B.,Williams, S.J.,Staskawicz, B.J.,Coleman, M.P.,Ve, T.,Dodds, P.N.,Kobe, B. (登録日: 2019-02-17, 公開日: 2019-09-04, 最終更新日: 2024-03-13)

• 主引用文献: Horsefield, S.,Burdett, H.,Zhang, X.,Manik, M.K.,Shi, Y.,Chen, J.,Qi, T.,Gilley, J.,Lai, J.S.,Rank, M.X.,Casey, L.W.,Gu, W.,Ericsson, D.J.,Foley, G.,Hughes, R.O.,Bosanac, T.,von Itzstein, M.,Rathjen, J.P.,Nanson, J.D.,Boden, M.,Dry, I.B.,Williams, S.J.,Staskawicz, B.J.,Coleman, M.P.,Ve, T.,Dodds, P.N.,Kobe, B.; NAD+cleavage activity by animal and plant TIR domains in cell death pathways.; Science, 365:793-799, 2019; PubMed: 31439792; DOI: 10.1126/science.aax1911

実験手法

X-RAY DIFFRACTION (1.75 Å)