6NZ7

Crystal structure of broadly neutralizing Influenza A antibody 429 B01 in complex with Hemagglutinin Hong Kong 1968

6NZ7 の概要

• エントリーDOI: 10.2210/pdb6nz7/pdb
• 分子名称: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 429 B01 FAB heavy chain, ... (6 entities in total)
• 機能のキーワード: antibody, influenza, neutralization, immune system
• 由来する生物種: Influenza A virus (strain A/Hong Kong/1/1968 H3N2); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 207650.54

構造登録者

Zhou, T.,Kwong, P.D. (登録日: 2019-02-13, 公開日: 2019-05-08, 最終更新日: 2020-07-29)

• 主引用文献: Matsuda, K.,Huang, J.,Zhou, T.,Sheng, Z.,Kang, B.H.,Ishida, E.,Griesman, T.,Stuccio, S.,Bolkhovitinov, L.,Wohlbold, T.J.,Chromikova, V.,Cagigi, A.,Leung, K.,Andrews, S.,Cheung, C.S.F.,Pullano, A.A.,Plyler, J.,Soto, C.,Zhang, B.,Yang, Y.,Joyce, M.G.,Tsybovsky, Y.,Wheatley, A.,Narpala, S.R.,Guo, Y.,Darko, S.,Bailer, R.T.,Poole, A.,Liang, C.J.,Smith, J.,Alexander, J.,Gurwith, M.,Migueles, S.A.,Koup, R.A.,Golding, H.,Khurana, S.,McDermott, A.B.,Shapiro, L.,Krammer, F.,Kwong, P.D.,Connors, M.; Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.; Sci Immunol, 4:-, 2019; PubMed: 31004012; DOI: 10.1126/sciimmunol.aau2710

実験手法

X-RAY DIFFRACTION (2.95 Å)