6NWG

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 3a

Summary for 6NWG

• Entry DOI: 10.2210/pdb6nwg/pdb
• Related: 6CVE
• Descriptor: ATP-dependent dethiobiotin synthetase BioD, [(1R,2R)-2-(2-methoxybenzene-1-carbonyl)cyclopentyl]propanedioic acid (3 entities in total)
• Functional Keywords: enzyme, nucleotide triphosphate binding, transferase, ligase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 4
• Total formula weight: 94061.59

Authors

Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B. (deposition date: 2019-02-06, release date: 2020-02-12, Last modification date: 2023-10-11)

• Primary citation: Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B.; Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 3a; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.939 Å)