6NUI

Human Guanylate Kinase

Summary for 6NUI

• Entry DOI: 10.2210/pdb6nui/pdb
• NMR Information: BMRB: 27151
• Descriptor: Guanylate kinase (1 entity in total)
• Functional Keywords: purine metabolism, atp:gmp-phosphotransferase, gmp kinase, unliganded, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 21891.73

Authors

Sabo, T.M.,Khan, N.,Ban, D.,Trigo-Mourino, P.,Carneiro, M.G.,Trent, J.O.,Konrad, M.,Lee, D. (deposition date: 2019-02-01, release date: 2019-06-26, Last modification date: 2024-05-01)

• Primary citation: Khan, N.,Shah, P.P.,Ban, D.,Trigo-Mourino, P.,Carneiro, M.G.,DeLeeuw, L.,Dean, W.L.,Trent, J.O.,Beverly, L.J.,Konrad, M.,Lee, D.,Sabo, T.M.; Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.; J.Biol.Chem., 294:11920-11933, 2019; PubMed: 31201273; DOI: 10.1074/jbc.RA119.009251

Experimental method

SOLUTION NMR