6NUB
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
Summary for 6NUB
Entry DOI | 10.2210/pdb6nub/pdb |
Descriptor | Pyruvate kinase PKM, 1,2-ETHANEDIOL, SERINE, ... (11 entities in total) |
Functional Keywords | glycolysis, gene regulation, phosphotransferase, serine, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 121982.91 |
Authors | Srivastava, D.,Nandi, S.,Dey, M. (deposition date: 2019-01-31, release date: 2019-08-21, Last modification date: 2023-10-11) |
Primary citation | Srivastava, D.,Nandi, S.,Dey, M. Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58:3669-3682, 2019 Cited by PubMed: 31386812DOI: 10.1021/acs.biochem.9b00349 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report