6NTP

PTP1B Domain of PTP1B-LOV2 Chimera

Summary for 6NTP

Entry DOI	10.2210/pdb6ntp/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1,NPH1-1, MAGNESIUM ION (3 entities in total)
Functional Keywords	protein tyrosine phosphatase, protein phosphorylation, signaling, diabetes, obesity, cancer, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	52174.41
Authors	Hongdusit, A.,Sankaran, B.,Zwart, P.H.,Fox, J.M. (deposition date: 2019-01-30, release date: 2020-01-22, Last modification date: 2023-10-11)
Primary citation	Hongdusit, A.,Zwart, P.H.,Sankaran, B.,Fox, J.M. Minimally disruptive optical control of protein tyrosine phosphatase 1B. Nat Commun, 11:788-788, 2020 Cited by PubMed: 32034150 DOI: 10.1038/s41467-020-14567-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation