6NSX

Yeast Hsh155 Ligand bound to Human Tat-SF1 Motif

Summary for 6NSX

• Entry DOI: 10.2210/pdb6nsx/pdb
• Descriptor: HIV Tat-specific factor 1, Hsh155, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: hiv tat-specific factor 1, tat-sf1, rna splicing factor, u2af homology motif, uhm, rna binding protein, u2af ligand motif, ulm, protein-peptide complex, pre-mrna splicing factor, hsh155, sf3b1, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 11936.27

Authors

Jenkins, J.L.,Leach, J.R.,Kielkopf, C.L. (deposition date: 2019-01-25, release date: 2019-06-05, Last modification date: 2023-10-11)

• Primary citation: Talkish, J.,Igel, H.,Hunter, O.,Horner, S.W.,Jeffery, N.N.,Leach, J.R.,Jenkins, J.L.,Kielkopf, C.L.,Ares, M.; Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.; Rna, 25:1020-1037, 2019; PubMed: 31110137; DOI: 10.1261/rna.070649.119

Experimental method

X-RAY DIFFRACTION (2 Å)