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6NPZ

Crystal structure of Akt1 (aa 123-480) kinase with a bisubstrate

Replaces:  6C0I
Summary for 6NPZ
Entry DOI10.2210/pdb6npz/pdb
Related6BUU
DescriptorRAC-alpha serine/threonine-protein kinase, bisubstrate, MANGANESE (II) ION, ... (7 entities in total)
Functional Keywordsakt1, rac-alpha serine/theronine-protein kinase, kinase, bisubstrate, transferase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight86853.74
Authors
Chu, N.,Cole, P.A.,Gabelli, S.B. (deposition date: 2019-01-18, release date: 2019-01-30, Last modification date: 2023-11-15)
Primary citationChu, N.,Salguero, A.L.,Liu, A.Z.,Chen, Z.,Dempsey, D.R.,Ficarro, S.B.,Alexander, W.M.,Marto, J.A.,Li, Y.,Amzel, L.M.,Gabelli, S.B.,Cole, P.A.
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Cell, 174:897-907.e14, 2018
Cited by
PubMed: 30078705
DOI: 10.1016/j.cell.2018.07.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.12 Å)
Structure validation

217705

数据于2024-03-27公开中

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