6NPR

Crystal structure of H-2Dd with C84-C139 disulfide in complex with gp120 derived peptide P18-I10

6NPR の概要

• エントリーDOI: 10.2210/pdb6npr/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE, ... (4 entities in total)
• 機能のキーワード: major histocompatibility complex, antigen presentation, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 90090.59

構造登録者

Toor, J.,McShan, A.C.,Tripathi, S.M.,Sgourakis, N.G. (登録日: 2019-01-18, 公開日: 2020-01-22, 最終更新日: 2023-10-11)

• 主引用文献: McShan, A.C.,Devlin, C.A.,Overall, S.A.,Park, J.,Toor, J.S.,Moschidi, D.,Flores-Solis, D.,Choi, H.,Tripathi, S.,Procko, E.,Sgourakis, N.G.; Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.; Proc.Natl.Acad.Sci.USA, 116:25602-25613, 2019; PubMed: 31796585; DOI: 10.1073/pnas.1915562116

実験手法

X-RAY DIFFRACTION (2.37 Å)