6NP9
PD-L1 IgV domain V76T with fragment
Summary for 6NP9
Entry DOI | 10.2210/pdb6np9/pdb |
Descriptor | Programmed cell death 1 ligand 1, SULFATE ION (3 entities in total) |
Functional Keywords | fragment-based screening, structure-based design, pd-l1 inhibitor, cancer drug discovery, immunotherapy, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 14734.71 |
Authors | |
Primary citation | Perry, E.,Mills, J.J.,Zhao, B.,Wang, F.,Sun, Q.,Christov, P.P.,Tarr, J.C.,Rietz, T.A.,Olejniczak, E.T.,Lee, T.,Fesik, S. Fragment-based screening of programmed death ligand 1 (PD-L1). Bioorg. Med. Chem. Lett., 29:786-790, 2019 Cited by PubMed: 30728114DOI: 10.1016/j.bmcl.2019.01.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.27 Å) |
Structure validation
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