6NN6
Structure of Dot1L-H2BK120ub nucleosome complex
Summary for 6NN6
Entry DOI | 10.2210/pdb6nn6/pdb |
EMDB information | 0458 0459 0460 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (8 entities in total) |
Functional Keywords | chromatin, structural biology, single particle, cryo-em, histone methyltransferase, nucleosome, dot1l, gene regulation |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 12 |
Total formula weight | 254261.76 |
Authors | Anderson, C.J.,Baird, M.R.,Hsu, A.,Barbour, E.H.,Koyama, Y.,Borgnia, M.J.,McGinty, R.K. (deposition date: 2019-01-14, release date: 2019-02-13, Last modification date: 2024-03-20) |
Primary citation | Anderson, C.J.,Baird, M.R.,Hsu, A.,Barbour, E.H.,Koyama, Y.,Borgnia, M.J.,McGinty, R.K. Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase. Cell Rep, 26:1681-1690.e5, 2019 Cited by PubMed: 30759380DOI: 10.1016/j.celrep.2019.01.058 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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