6NIL

cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex

Summary for 6NIL

• Entry DOI: 10.2210/pdb6nil/pdb
• EMDB information: 9380
• Descriptor: DNA dC->dU-editing enzyme APOBEC-3F, Core-binding factor subunit beta, Virion infectivity factor, ... (4 entities in total)
• Functional Keywords: human antiviral restriction factor, hiv viral protein, antiviral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 236343.30

Authors

Hu, Y.,Xiong, Y. (deposition date: 2018-12-29, release date: 2019-12-11, Last modification date: 2024-03-20)

• Primary citation: Hu, Y.,Desimmie, B.A.,Nguyen, H.C.,Ziegler, S.J.,Cheng, T.C.,Chen, J.,Wang, J.,Wang, H.,Zhang, K.,Pathak, V.K.,Xiong, Y.; Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.; Nat.Struct.Mol.Biol., 26:1176-1183, 2019; PubMed: 31792451; DOI: 10.1038/s41594-019-0343-6

Experimental method

ELECTRON MICROSCOPY (3.9 Å)