6NF0

Nocturnin with bound NADPH substrate

Summary for 6NF0

Entry DOI	10.2210/pdb6nf0/pdb
Descriptor	Nocturnin, CALCIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	circadian clock, metabolism, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	36275.60
Authors	Estrella, M.A.,Du, J.,Korennykh, A. (deposition date: 2018-12-18, release date: 2019-05-01, Last modification date: 2023-10-11)
Primary citation	Estrella, M.A.,Du, J.,Chen, L.,Rath, S.,Prangley, E.,Chitrakar, A.,Aoki, T.,Schedl, P.,Rabinowitz, J.,Korennykh, A. The metabolites NADP+and NADPH are the targets of the circadian protein Nocturnin (Curled). Nat Commun, 10:2367-2367, 2019 Cited by PubMed: 31147539 DOI: 10.1038/s41467-019-10125-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation