6NCT

Structure of p110alpha/niSH2 - vector data collection

Summary for 6NCT

• Entry DOI: 10.2210/pdb6nct/pdb
• Related: 4OVU
• Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... (4 entities in total)
• Functional Keywords: pi3k, kinase, phosphatidylinositol 4, 5-bisphosphate 3-kinase alpha isoform, p110, p85, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 162022.01

Authors

Miller, M.S.,Maheshwari, S.,Amzel, L.M.,Gabelli, S.B. (deposition date: 2018-12-12, release date: 2019-02-06, Last modification date: 2023-10-11)

• Primary citation: Miller, M.S.,Maheshwari, S.,Shi, W.,Gao, Y.,Chu, N.,Soares, A.S.,Cole, P.A.,Amzel, L.M.,Fuchs, M.R.,Jakoncic, J.,Gabelli, S.B.; Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II.; Molecules, 24:-, 2019; PubMed: 30704096; DOI: 10.3390/molecules24030496

Experimental method

X-RAY DIFFRACTION (3.35 Å)