6NB9
Amyloid-Beta (20-34) with L-isoaspartate 23
Summary for 6NB9
Entry DOI | 10.2210/pdb6nb9/pdb |
EMDB information | 0405 |
Descriptor | Amyloid-beta A4 protein (2 entities in total) |
Functional Keywords | protofilament, 2 sub 1 screw symmetry, post-translational modification, isoaspartate, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 1491.67 |
Authors | Sawaya, M.R.,Warmack, R.A.,Boyer, D.R.,Zee, C.T.,Richards, L.S.,Cascio, D.,Gonen, T.,Clarke, S.G.,Eisenberg, D.S. (deposition date: 2018-12-06, release date: 2019-08-07, Last modification date: 2022-09-07) |
Primary citation | Warmack, R.A.,Boyer, D.R.,Zee, C.T.,Richards, L.S.,Sawaya, M.R.,Cascio, D.,Gonen, T.,Eisenberg, D.S.,Clarke, S.G. Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun, 10:3357-3357, 2019 Cited by PubMed: 31350392DOI: 10.1038/s41467-019-11183-z PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (1.05 Å) |
Structure validation
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