6N9O
Crystal structure of human GSDMD
Summary for 6N9O
Entry DOI | 10.2210/pdb6n9o/pdb |
Descriptor | Gasdermin-D (1 entity in total) |
Functional Keywords | pyroptosis, gasdermin d, inflammasome, autoinhibition, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 211979.84 |
Authors | Liu, Z.,Wang, C.,Yang, J.,Xiao, T.S. (deposition date: 2018-12-03, release date: 2019-06-05, Last modification date: 2023-10-11) |
Primary citation | Liu, Z.,Wang, C.,Yang, J.,Zhou, B.,Yang, R.,Ramachandran, R.,Abbott, D.W.,Xiao, T.S. Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization. Immunity, 51:43-, 2019 Cited by PubMed: 31097341DOI: 10.1016/j.immuni.2019.04.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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