6N8Q
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 2.
Summary for 6N8Q
Entry DOI | 10.2210/pdb6n8q/pdb |
Descriptor | Lethal(2) giant larvae protein homolog 2, CHLORIDE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | lgl, polarity, beta propeller, lipid binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 109402.66 |
Authors | Almagor, L.,Weis, W.I. (deposition date: 2018-11-30, release date: 2019-05-08, Last modification date: 2024-03-13) |
Primary citation | Almagor, L.,Ufimtsev, I.S.,Ayer, A.,Li, J.,Weis, W.I. Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2. Proc.Natl.Acad.Sci.USA, 116:10804-10812, 2019 Cited by PubMed: 31088962DOI: 10.1073/pnas.1821514116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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