6N8D
Crystal structure of GII.4 2002 norovirus P domain in complex with neutralizing human antibody A1431
Summary for 6N8D
Entry DOI | 10.2210/pdb6n8d/pdb |
Related | 6N81 |
Descriptor | Major capsid protein, A1431 Fab light chain, A1431 Fab heavy chain (3 entities in total) |
Functional Keywords | norovirus, human antibody, fab, complex, neutralizing, immune system |
Biological source | Norovirus Hu/GII.4/Farmington Hills/2004/USA More |
Total number of polymer chains | 6 |
Total formula weight | 164775.61 |
Authors | Changela, A.,Verardi, R.,Kwong, P.D. (deposition date: 2018-11-29, release date: 2019-06-19, Last modification date: 2023-10-11) |
Primary citation | Lindesmith, L.C.,McDaniel, J.R.,Changela, A.,Verardi, R.,Kerr, S.A.,Costantini, V.,Brewer-Jensen, P.D.,Mallory, M.L.,Voss, W.N.,Boutz, D.R.,Blazeck, J.J.,Ippolito, G.C.,Vinje, J.,Kwong, P.D.,Georgiou, G.,Baric, R.S. Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Immunity, 50:1530-1541.e8, 2019 Cited by PubMed: 31216462DOI: 10.1016/j.immuni.2019.05.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report