6N3Y
Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Guanosine
Summary for 6N3Y
Entry DOI | 10.2210/pdb6n3y/pdb |
Descriptor | Histidine triad nucleotide-binding protein 1, 5'-O-{[2-(1H-indol-3-yl)ethyl]carbamoyl}guanosine, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | hint, histidine triad, hit, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 28732.73 |
Authors | Strom, A.M.,Finzel, B.C. (deposition date: 2018-11-16, release date: 2019-09-18, Last modification date: 2023-10-11) |
Primary citation | Shah, R.M.,Peterson, C.,Strom, A.,Dillenburg, M.,Finzel, B.,Kitto, K.F.,Fairbanks, C.,Wilcox, G.,Wagner, C.R. Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chem Neurosci, 10:4385-4393, 2019 Cited by PubMed: 31503445DOI: 10.1021/acschemneuro.9b00432 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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