6N2M
NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil
Summary for 6N2M
Entry DOI | 10.2210/pdb6n2m/pdb |
Related | 6N2P |
NMR Information | BMRB: 30543 |
Descriptor | Caspase recruitment domain-containing protein 9, ZINC ION (2 entities in total) |
Functional Keywords | innate immunity, coiled-coil, autoinhibition, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 32363.73 |
Authors | Holliday, M.J.,Fairbrother, W.J.,Dueber, E.C. (deposition date: 2018-11-13, release date: 2019-07-17, Last modification date: 2024-05-15) |
Primary citation | Holliday, M.J.,Witt, A.,Rodriguez Gama, A.,Walters, B.T.,Arthur, C.P.,Halfmann, R.,Rohou, A.,Dueber, E.C.,Fairbrother, W.J. Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation. Nat Commun, 10:3070-3070, 2019 Cited by PubMed: 31296852DOI: 10.1038/s41467-019-10953-z PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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