6N2M
NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 200 |
| Chain | Residue |
| A | ASP3 |
| A | GLU5 |
| A | CYS10 |
| A | HIS73 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue ZN B 200 |
| Chain | Residue |
| B | ASP3 |
| B | CYS10 |
| B | HIS73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 184 |
| Details | Domain: {"description":"CARD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00046","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Region: {"description":"Linker","evidences":[{"source":"PubMed","id":"31296852","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31296852","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6N2M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30206119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31296852","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6E27","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N2M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9EPY0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26488816","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31296852","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33093067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
