6N0Z
Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase N20K H194M mutant complexed with (R)-MVAPP
Summary for 6N0Z
Entry DOI | 10.2210/pdb6n0z/pdb |
Descriptor | Diphosphomevalonate decarboxylase, (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID (3 entities in total) |
Functional Keywords | lyase |
Biological source | Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1) |
Total number of polymer chains | 6 |
Total formula weight | 216365.32 |
Authors | Noel, J.P.,Thomas, S.T.,Louie, G.V. (deposition date: 2018-11-07, release date: 2019-07-17, Last modification date: 2023-10-11) |
Primary citation | Thomas, S.T.,Louie, G.V.,Lubin, J.W.,Lundblad, V.,Noel, J.P. Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14:1767-1779, 2019 Cited by PubMed: 31268677DOI: 10.1021/acschembio.9b00322 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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