6N0K

The complex of CCG-257081 bound to pirin

Summary for 6N0K

• Entry DOI: 10.2210/pdb6n0k/pdb
• Descriptor: Pirin, FE (III) ION, (3R)-N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyridin-4-yl)benzene-1-carbonyl]piperidine-3-carboxamide, ... (5 entities in total)
• Functional Keywords: beta barrel, iron-binding, co-transcription factor, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34211.71

Authors

Lisabeth, E.M.,Jin, X.,Neubig, R. (deposition date: 2018-11-07, release date: 2019-07-10, Last modification date: 2023-10-11)

• Primary citation: Lisabeth, E.M.,Kahl, D.,Gopallawa, I.,Haynes, S.E.,Misek, S.A.,Campbell, P.L.,Dexheimer, T.S.,Khanna, D.,Fox, D.A.,Jin, X.,Martin, B.R.,Larsen, S.D.,Neubig, R.R.; Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds; ACS Pharmacol Transl Sci, 2:92-100, 2019

Experimental method

X-RAY DIFFRACTION (1.46 Å)