6MYL

The Prp8 intein-cisplatin complex

Summary for 6MYL

• Entry DOI: 10.2210/pdb6myl/pdb
• Related: 6MWY
• Descriptor: Pre-mRNA-processing-splicing factor 8, PLATINUM (II) ION (2 entities in total)
• Functional Keywords: prp8, intein, cisplatin, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Cryptococcus gattii serotype B (Filobasidiella gattii)
• Total number of polymer chains: 3
• Total formula weight: 75097.62

Authors

Li, Z.,Li, H. (deposition date: 2018-11-01, release date: 2019-11-06, Last modification date: 2023-11-15)

• Primary citation: Li, Z.,Fu, B.,Green, C.M.,Liu, B.,Zhang, J.,Lang, Y.,Chaturvedi, S.,Belfort, M.,Liao, G.,Li, H.; Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.; Emerg Microbes Infect, 8:895-908, 2019; PubMed: 31223062; DOI: 10.1080/22221751.2019.1625727

Experimental method

X-RAY DIFFRACTION (3.06 Å)