Crystal structure of pRO-2.5

Summary for 6MSR

DescriptorpRO-2.5 (2 entities in total)
Functional Keywordsde novo protein, computational design, helical bundle
Biological sourcesynthetic construct
Total number of polymer chains3
Total molecular weight25442.12
Bick, M.J.,Boyken, S.E.,Baker, D. (deposition date: 2018-10-17, release date: 2019-05-08, Last modification date: 2019-05-29)
Primary citation
Boyken, S.E.,Benhaim, M.A.,Busch, F.,Jia, M.,Bick, M.J.,Choi, H.,Klima, J.C.,Chen, Z.,Walkey, C.,Mileant, A.,Sahasrabuddhe, A.,Wei, K.Y.,Hodge, E.A.,Byron, S.,Quijano-Rubio, A.,Sankaran, B.,King, N.P.,Lippincott-Schwartz, J.,Wysocki, V.H.,Lee, K.K.,Baker, D.
De novo design of tunable, pH-driven conformational changes.
Science, 364:658-664, 2019
PubMed: 31097662 (PDB entries with the same primary citation)
DOI: 10.1126/science.aav7897
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26430 1.9% 4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution