6MSO

Crystal structure of mitochondrial fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate

6MSO の概要

• エントリーDOI: 10.2210/pdb6mso/pdb
• 分子名称: fumarate hydratase, IRON/SULFUR CLUSTER, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: inhibitor, mitochondrial, fumarate hydratase, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 263979.52

構造登録者

Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. (登録日: 2018-10-17, 公開日: 2019-01-30, 最終更新日: 2023-10-11)

• 主引用文献: Feliciano, P.R.,Drennan, C.L.,Nonato, M.C.; Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.; ACS Chem. Biol., 14:266-275, 2019; PubMed: 30645090; DOI: 10.1021/acschembio.8b00972

実験手法

X-RAY DIFFRACTION (2.053 Å)