6MR9
E. coli DHFR complex with a reaction intermediate
Summary for 6MR9
| Entry DOI | 10.2210/pdb6mr9/pdb |
| Related | 6CW7 6CXK |
| Descriptor | Dihydrofolate reductase, CHLORIDE ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | dhfr, dihydrofolate reductase, tetrahydrofolate, complex, reaction intermediate, oxidoreductase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 19497.23 |
| Authors | Cao, H.,Rodrigues, J.,Benach, J.,Frommelt, A.,Morisco, L.,Koss, J.,Shakhnovich, E.,Skolnick, J. (deposition date: 2018-10-12, release date: 2019-05-15, Last modification date: 2023-10-11) |
| Primary citation | Cao, H.,Skolnick, J. Time-resolved x-ray crystallography capture of a slow reaction tetrahydrofolate intermediate. Struct Dyn., 6:024701-024701, 2019 Cited by PubMed: 30868089DOI: 10.1063/1.5086436 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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