6MPW
De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-1
Summary for 6MPW
Entry DOI | 10.2210/pdb6mpw/pdb |
Descriptor | mini-eVgL membrane protein, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE (2 entities in total) |
Functional Keywords | de novo design, membrane protein, pentameric bundle, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 5 |
Total formula weight | 17289.40 |
Authors | Mravic, M.,Liu, L.,DeGrado, W.F. (deposition date: 2018-10-08, release date: 2019-04-03, Last modification date: 2023-10-11) |
Primary citation | Mravic, M.,Thomaston, J.L.,Tucker, M.,Solomon, P.E.,Liu, L.,DeGrado, W.F. Packing of apolar side chains enables accurate design of highly stable membrane proteins. Science, 363:1418-1423, 2019 Cited by PubMed: 30923216DOI: 10.1126/science.aav7541 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report