6MP4
Human liver FABP1 bound to tetrahydrocannabinol
Summary for 6MP4
Entry DOI | 10.2210/pdb6mp4/pdb |
Descriptor | Fatty acid-binding protein, liver, MALONATE ION, (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, ... (4 entities in total) |
Functional Keywords | fatty acid binding protein cannabinoid, lipid binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 135530.46 |
Authors | McGoldrick, L.L.,Giuliano, C.J.,Elmes, M.W.,Deutsch, D.G.,Kaczocha, M.,Glynn, S.E. (deposition date: 2018-10-05, release date: 2019-11-13, Last modification date: 2024-04-03) |
Primary citation | Elmes, M.W.,Prentis, L.E.,McGoldrick, L.L.,Giuliano, C.J.,Sweeney, J.M.,Joseph, O.M.,Che, J.,Carbonetti, G.S.,Studholme, K.,Deutsch, D.G.,Rizzo, R.C.,Glynn, S.E.,Kaczocha, M. FABP1 controls hepatic transport and biotransformation of Delta 9 -THC. Sci Rep, 9:7588-7588, 2019 Cited by PubMed: 31110286DOI: 10.1038/s41598-019-44108-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.502 Å) |
Structure validation
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