6MLK

Structure of Thioesterase from DEBS with a thioesterase-specific antibody

Summary for 6MLK

Entry DOI	10.2210/pdb6mlk/pdb
Descriptor	6-deoxyerythronolide-B synthase EryA3, modules 5 and 6, Light chain of Fab 3A6, Heavy chain of Fab 3A6, ... (5 entities in total)
Functional Keywords	6-deoxyerythronolide b synthase, thioesterase, monoclonal antibody, transferase
Biological source	Saccharopolyspora erythraea More
Total number of polymer chains	3
Total formula weight	84440.60
Authors	Mathews, I.I.,Li, X.,Khosla, C. (deposition date: 2018-09-27, release date: 2018-10-17, Last modification date: 2023-10-11)
Primary citation	Li, X.,Sevillano, N.,La Greca, F.,Hsu, J.,Mathews, I.I.,Matsui, T.,Craik, C.S.,Khosla, C. Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase. Biochemistry, 57:6201-6208, 2018 Cited by PubMed: 30289692 DOI: 10.1021/acs.biochem.8b00886 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation