6MLK

Structure of Thioesterase from DEBS with a thioesterase-specific antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	6-deoxyerythronolide-B synthase EryA3, modules 5 and 6	polymer	300	32112.8	1	UniProt (Q03133) Pfam (PF00975)	Saccharopolyspora erythraea	DEBS 3,6-deoxyerythronolide B synthase III,Erythronolide synthase,ORF C
2	B (L)	Light chain of Fab 3A6	polymer	235	25772.8	1		Homo sapiens
3	C (H)	Heavy chain of Fab 3A6	polymer	251	26519.6	1		Homo sapiens
4	D (H)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	E, F, G (A, L, H)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A: 4 - 283 (UniProt: Q03133)

PDB	External Database	Details
Met 1	-	initiating methionine
Ala 2	-	expression tag
Ser 3	-	expression tag
Ser 284	-	expression tag
Ser 285	-	expression tag
Val 286	-	expression tag
Asp 287	-	expression tag
Lys 288	-	expression tag
Leu 289	-	expression tag
Ala 290	-	expression tag
Ala 291	-	expression tag
Ala 292	-	expression tag
Leu 293	-	expression tag
Glu 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	84405.1
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	84440.6

*Water molecules are not included.