6MKS
Cryo-EM structure of NLRC4-CARD filament
Summary for 6MKS
| Entry DOI | 10.2210/pdb6mks/pdb |
| EMDB information | 9137 |
| Descriptor | Chimera protein of NLR family CARD domain-containing protein 4 and EGFP (1 entity in total) |
| Functional Keywords | nlrc4, helical assembly, inflammasome, protein fibril |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 31 |
| Total formula weight | 1198732.96 |
| Authors | Zheng, W.,Matyszewski, M.,Sohn, J.,Egelman, E.H. (deposition date: 2018-09-26, release date: 2018-11-07, Last modification date: 2024-03-13) |
| Primary citation | Matyszewski, M.,Zheng, W.,Lueck, J.,Antiochos, B.,Egelman, E.H.,Sohn, J. Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly. J. Biol. Chem., 293:20240-20248, 2018 Cited by PubMed: 30385506DOI: 10.1074/jbc.RA118.006050 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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