6MKS

Cryo-EM structure of NLRC4-CARD filament

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, B, BA, C... (A, B, C, D, E...)	Chimera protein of NLR family CARD domain-containing protein 4 and EGFP	polymer	340	38668.8	31	UniProt (Q9NPP4) UniProt (A0A1V0D974) Pfam (PF00619) Pfam (PF01353) UniProt (by SIFTS) (P42212)	Homo sapiens (Human)	CARD,LRR,and NACHT-containing protein,Clan protein,Caspase recruitment domain-containing protein 12,Ice protease-activating factor,Ipaf

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e: 1 - 96 (UniProt: Q9NPP4)

PDB	External Database	Details
Gly -2	-	expression tag
Thr -1	-	expression tag
Gly 0	-	expression tag
Lys 97	-	linker
Leu 98	-	linker

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e: 99 - 330 (UniProt: A0A1V0D974)

PDB	External Database	Details
Glu 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
His 335	-	expression tag
His 336	-	expression tag
His 337	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	31
	Total formula weight	1198733.0
All*	Total formula weight	1198733.0

*Water molecules are not included.